Is There Any Role of Pulmonary Endarterectomy in Pulmonary Arterial Hydatidosis?


Erkilinç A., Ermerak N. O., Zengin A., Olgun Yildizeli Ş., Mutlu B. L., Karakoç A. Z., ...Daha Fazla

ANNALS OF THORACIC SURGERY, cilt.114, sa.6, ss.2093-2099, 2022 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 114 Sayı: 6
  • Basım Tarihi: 2022
  • Doi Numarası: 10.1016/j.athoracsur.2021.10.035
  • Dergi Adı: ANNALS OF THORACIC SURGERY
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, CAB Abstracts, EMBASE, MEDLINE, Veterinary Science Database
  • Sayfa Sayıları: ss.2093-2099
  • Marmara Üniversitesi Adresli: Evet

Özet

BACKGROUND Hydatid cyst is a zoonosis caused by Echinococcus granulosis. Pulmonary artery involvement is a rare condition. The aim of this study was to review the investigators' experience with the surgical treatment of pulmonary arterial hydatidosis. METHODS Data were collected prospectively for consecutive patients who underwent pulmonary endarterectomy (PEA) and who had a diagnosis of hydatidosis at or after PEA. RESULTS A total of 8 patients (2 male and 6 female; mean age, 31.25 +/- 13.68 years) with hydatidosis were defined. Only 1 patient presented with hemoptysis, whereas the rest of the patients reported exertional dyspnea as their main symptom. Cardiac hydatidosis associated with pulmonary arterial involvement was noted in 1 patient. The mean time interval for duration of disease was 12 +/- 24.29 months before PEA. Mortality was observed in 2 patients as a result of massive hemoptysis in 1 patient and right-sided heart failure in the other. No anaphylactic reaction was observed. Significant difference was detected in mean pulmonary vascular resistance as a decline from 442.38 +/- 474.20 dyn/s/cm- 5 to 357.25 +/- 285.34 dyn/s/cm-5 after PEA (P [ .011). Two patients had recurrence of the disease after a median follow-up of 9.1 months All survivors improved to New York Heart Association functional classes I and II. CONCLUSION Pulmonary arterial hydatidosis may mimic chronic thromboembolic pulmonary hypertension, and in these patients the diagnosis can be made with PEA. Pulmonary endarterectomy may be a therapeutic option for patients who do not respond to medical therapy if the cystic lesions are surgically accessible. PEA should be performed only in expert centers because of the high risk of perioperative morbidity, mortality, and postoperative recurrence. (C)2022 by The Society of Thoracic Surgeons