The protective effect of oxytocin on renal ischemia/reperfusion injury in rats

Tugtepe H., Sener G. , Biyikli N. K. , Yuksel M. , Cetinel S. , Gedik N., ...More

REGULATORY PEPTIDES, vol.140, no.3, pp.101-108, 2007 (Journal Indexed in SCI) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 140 Issue: 3
  • Publication Date: 2007
  • Doi Number: 10.1016/j.regpep.2006.11.026
  • Title of Journal : REGULATORY PEPTIDES
  • Page Numbers: pp.101-108
  • Keywords: oxytocin, ischemia/reperfusion, kidney, lipid peroxidation, myeloperoxidase, glutathione, ISCHEMIA-REPERFUSION INJURY, NITRIC-OXIDE SYNTHASE, NEUTROPHIL-DEPENDENT MECHANISM, ATRIAL-NATRIURETIC-PEPTIDE, ADHESION MOLECULES, FAILURE, RECEPTORS, KIDNEY, MYELOPEROXIDASE, INFLAMMATION

Abstract

Aim: Oxytocin was previously shown to have anti-inflammatory effects in different inflammation models. The major objective of the present study was to evaluate the protective role of oxytocin (OT) in protecting the kidney against ischemia/reperfusion (I/R) injury.