Linezolid treatment of shunt-related cerebrospinal fluid infections in children Clinical article

Yilmaz A., Dalgic N., Musluman M., SANCAR M., Colak I., Aydin Y.

JOURNAL OF NEUROSURGERY-PEDIATRICS, cilt.5, sa.5, ss.443-448, 2010 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 5 Sayı: 5
  • Basım Tarihi: 2010
  • Doi Numarası: 10.3171/2009.12.peds09421
  • Dergi Adı: JOURNAL OF NEUROSURGERY-PEDIATRICS
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.443-448
  • Anahtar Kelimeler: linezad, ventriculoperitoneal shunt, infection, multidrug resistance, RESISTANT ENTEROCOCCUS-FAECIUM, NERVOUS-SYSTEM INFECTIONS, STAPHYLOCOCCUS-AUREUS, BACTERIAL BIOFILMS, VANCOMYCIN, MENINGITIS, VENTRICULITIS, EXPERIENCE, MANAGEMENT, SUSCEPTIBILITY
  • Marmara Üniversitesi Adresli: Evet

Özet

Object. The emergence of multidrug-resistant bacteria as a cause of ventriculoperitoneal (VP) shunt infection is a disconcerting phenomenon that often requires the use of alternative antimicrobial agents due to resistance against commonly used medications. Linezolid, a member of a new class of antimicrobial agents, has good activity against virtually all important gram-positive pathogens, including multidrug-resistant gram-positive pathogens. The object of this article is to report a single-center experience with linezolid treatment in 6 young patients with VP shunt infections caused by drug-resistant strains.