The Effects of Nitric Oxide and Inhibitor, and Combination of Albendazole and Praziquantel On Liver in Mice Injected with Echinococcus granulosus Larvae

Kandil A., GARGILI KELEŞ A. , Balci H., Tansel C. D.

ACTA TROPICA, vol.219, 2021 (Journal Indexed in SCI) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 219
  • Publication Date: 2021
  • Doi Number: 10.1016/j.actatropica.2021.105917
  • Title of Journal : ACTA TROPICA
  • Keywords: Echinococcus granulosus, hydatidosis, liver, nitric oxide, anthelmintic drugs, IN-VITRO, PHARMACOKINETIC INTERACTION, LIPID-PEROXIDATION, HUMAN HYDATIDOSIS, IFN-GAMMA, TNF-ALPHA, CYSTS, NO, EXPRESSION, SULFOXIDE


In this study, the role of nitric oxide (NO) in the pathogenesis of hydatidosis and the interaction with effects of anthelmintic drugs, albendazole and praziquantel, were examined in larval infection caused by protoscolices obtained from hydatid cysts of sheep liver in Albino Balb/c mice.