MUSCARINIC RECEPTOR SUBTYPES OF GUINEA-PIG GALLBLADDER SMOOTH-MUSCLE


KURTEL H., YEGEN B. , DEDEOGLU A., ULUSOY N., OKTAY S.

ARCHIVES INTERNATIONALES DE PHARMACODYNAMIE ET DE THERAPIE, vol.308, pp.39-46, 1990 (Journal Indexed in SCI) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 308
  • Publication Date: 1990
  • Title of Journal : ARCHIVES INTERNATIONALES DE PHARMACODYNAMIE ET DE THERAPIE
  • Page Numbers: pp.39-46

Abstract

The antagonism of acetylcholine-induced contractions of guinea-pig gallbladder and ileum smooth muscle strips via various antagonists has been investigated in order to find out the muscarinic receptor subtype(s) of gallbladder smooth muscle. Atropine, pirenzepine, 4-DAMP and AF-DX 116 were used as nonselective, M1-selective, M1- and smooth muscle M3-selective and cardiac M2-selective muscarinic antagonists, respectively.