The protective effects of tacrolimus on rat uteri exposed to ischemia-reperfusion injury: a biochemical and histopathologic evaluation

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Sahin S., BİNGÖL ÖZAKPINAR Ö., AK K., Eroglu M., Acikel M., TETİK Ş., ...More

FERTILITY AND STERILITY, vol.101, no.4, pp.1176-1182, 2014 (SCI-Expanded)

• Publication Type: Article / Article
• Volume: 101 Issue: 4
• Publication Date: 2014
• Doi Number: 10.1016/j.fertnstert.2013.12.044
• Journal Name: FERTILITY AND STERILITY
• Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
• Page Numbers: pp.1176-1182
• Keywords: Ischemia-reperfusion injury, tacrolimus, uterus, rat, transplantation, WARM ISCHEMIA, LIVER-TRANSPLANTATION, ISCHEMIA/REPERFUSION INJURY, OXIDATIVE STRESS, FK506, CYCLOSPORINE, GLUTATHIONE, PREGNANCY, COLD, MECHANISMS
• Marmara University Affiliated: Yes

Abstract

Objective: To evaluate the effects of the immunosuppressant tacrolimus as an antioxidant and analyze the histopathologic changes in rat uteri exposed to experimental ischemia-reperfusion (I/R) injury.