The antioxidant and anti-inflammatory efficiency of hyaluronic acid after third molar extraction

GÖÇMEN G., GÖNÜL O., OKTAY N. Ş., YARAT A., Goker K.

JOURNAL OF CRANIO-MAXILLOFACIAL SURGERY, cilt.43, sa.7, ss.1033-1037, 2015 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 43 Sayı: 7
  • Basım Tarihi: 2015
  • Doi Numarası: 10.1016/j.jcms.2015.04.022
  • Dergi Adı: JOURNAL OF CRANIO-MAXILLOFACIAL SURGERY
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.1033-1037
  • Anahtar Kelimeler: Hyaluronic acid, Third molar extraction, Wound healing, DAMAGE, SURGERY, REPAIR, TISSUE
  • Marmara Üniversitesi Adresli: Evet

Özet

Purpose: Hyaluronic acid (HA) has a number of clinical applications in current practice. Therefore, correlation of HA with free radicals and inflammatory cells is clinically important. The purpose of this study is to measure the efficacy of high molecular weight HA on the oxidative stress of oral wounds (glutathione (GSH) and lipid peroxidation (LPO) levels), the inflammatory reaction (leucocytes, collagen and angiogenesis content), pain (visual analogue scale (VAS) records) and trismus (maximum interincisal opening (MIO) records) after third molar (M3) extraction.