Cerebellar liponeurocytoma/lipidized medulloblastoma - Case report and review of the literature

Aker F., Ozkara S., Eren P., Peker O., Armagan S., Hakan T.

JOURNAL OF NEURO-ONCOLOGY, cilt.71, sa.1, ss.53-59, 2005 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 71 Sayı: 1
  • Basım Tarihi: 2005
  • Doi Numarası: 10.1007/s11060-004-9172-4
  • Dergi Adı: JOURNAL OF NEURO-ONCOLOGY
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.53-59
  • Anahtar Kelimeler: adipose tissue, cerebellar neoplasm, lipidization, liponeurocytoma, medulloblastoma, LIPOMATOUS MEDULLOBLASTOMA, NEUROECTODERMAL TUMOR, FAVORABLE PROGNOSIS, CLINICOPATHOLOGICAL ENTITY, LIPIDIZED MEDULLOBLASTOMA, ADULT PATIENTS, DNA-PLOIDY, DIFFERENTIATION
  • Marmara Üniversitesi Adresli: Hayır

Özet

Cerebellar liponeurocytoma that has been recently identified as a distinct entity by the World Health Organization is characterized by areas of lipomatous differentiation and apparently by a favorable prognosis. In this paper, we described a case of 49-year-old female showing progressive clinical course inspite of a low labeling/mitotic index. We also review the relevant literature. Although, basically all reported cases share a similar histological pattern, i.e. focal accumulations of adiposities in an otherwise typical small cell tumor like central neurocytoma, some clinical properties such as (age, proliferative potential, therapy and survival) are not uniform. The exact biological behavior of this special variant tumor is established. Yet, this needs further confirmation on a large number of cases with longer follow-up periods.