Cytotoxic Antibody Detection by Means of Flow-Cytometric Cross-Match


Bilgen T., Ata P. , Tozkir J., Tozkir H., Titiz M. I.

TRANSPLANTATION PROCEEDINGS, vol.49, no.3, pp.440-444, 2017 (Journal Indexed in SCI) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 49 Issue: 3
  • Publication Date: 2017
  • Doi Number: 10.1016/j.transproceed.2017.01.016
  • Title of Journal : TRANSPLANTATION PROCEEDINGS
  • Page Numbers: pp.440-444

Abstract

Background. Complement-dependent lymphocytotoxicity (CDC-XM) and flowcytometric (FCXM) cross-match are analyzed individually for each donor and recipient pair, because these techniques have fundamental differences for the evaluation of histocompatibility. Lately, cytotoxic flow-cytometric cross-match (cFCXM) has been developed as an alternative to both CDC-XM and FCXM techniques. We evaluated the limits of cFCXM with the use of different positive serum dilutions.