Physical-chemical characterization and biological assessment of simple and lithium-doped biological-derived hydroxyapatite thin films for a new generation of metallic implants


Popescu A. C. , Florian P., Stan G., Popescu-Pelin G., Zgura I., Enculescu M., ...More

APPLIED SURFACE SCIENCE, vol.439, pp.724-735, 2018 (Journal Indexed in SCI) identifier identifier

  • Publication Type: Article / Article
  • Volume: 439
  • Publication Date: 2018
  • Doi Number: 10.1016/j.apsusc.2018.01.008
  • Title of Journal : APPLIED SURFACE SCIENCE
  • Page Numbers: pp.724-735
  • Keywords: Biological-derived hydroxyapatite, Lithium doping, Pulsed Laser Deposition, Sustainable resources, In vitro assessment, PULSED-LASER DEPOSITION, MESENCHYMAL STEM-CELLS, CARBONATED HYDROXYAPATITE, SYNTHETIC HYDROXYAPATITE, BIOMEDICAL APPLICATIONS, PHOSPHATE CERAMICS, BONE REGENERATION, SURFACE-ENERGY, COATINGS, TITANIUM

Abstract

We report on the synthesis by PLD of simple and lithium-doped biological-origin hydroxyapatite (HA) films. The role of doping reagents (Li2CO3, Li3PO4) on the morphology, structure, chemical composition, bonding strength and cytocompatibility of the films was investigated.