Effect of intravenous zoledronic acid infusion on electrocardiographic parameters in patients with osteoporosis

Aktas, I.; Nazikoglu, C.; Kepez, ALPER; Ozkan, F.; Kaysin, M.; Akpinar, P.; Dogan, Z.; Ileri, C.; Saymaz, S.; Erdogan, O.

doi:10.1007/s00198-016-3684-6

Effect of intravenous zoledronic acid infusion on electrocardiographic parameters in patients with osteoporosis

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Aktas I., Nazikoglu C., Kepez A., Ozkan F. U., Kaysin M. Y., Akpinar P., ...More

OSTEOPOROSIS INTERNATIONAL, vol.27, pp.3543-3547, 2016 (SCI-Expanded)

Publication Type: Article / Article
Volume: 27
Publication Date: 2016
Doi Number: 10.1007/s00198-016-3684-6
Journal Name: OSTEOPOROSIS INTERNATIONAL
Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
Page Numbers: pp.3543-3547
Marmara University Affiliated: Yes

Abstract

We evaluated the effects of zoledronic acid (ZA) therapy on electrocardiographic (ECG) parameters for the first time in the literature. Measurements were performed on ECGs obtained before and after ZA infusion on the same day as well as 1 month after the infusion. ZA infusion did not have any short- or long-term effect on any parameter that might be associated with the tendency for atrial fibrillation or ventricular arrhythmias.