Determination of CYP2C19 Polymorphism, Side Effects, and Medication Adherence in Patients Who have Utilized Selective Serotonin Reuptake Inhibitors

Deniz, Semanur; SANCAR, MESUT; OKUYAN, BETÜL; ATA, PINAR; BİNGÖL ÖZAKPINAR, ÖZLEM; Talas, Anil; Gunes, Tufan; Caliskan, Mecit; Izzettin, Fikret

doi:10.5455/bcp.20151003060610

Determination of CYP2C19 Polymorphism, Side Effects, and Medication Adherence in Patients Who have Utilized Selective Serotonin Reuptake Inhibitors

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Deniz S., SANCAR M., OKUYAN B., ATA P., BİNGÖL ÖZAKPINAR Ö., Talas A., ...More

KLINIK PSIKOFARMAKOLOJI BULTENI-BULLETIN OF CLINICAL PSYCHOPHARMACOLOGY, vol.26, no.2, pp.152-160, 2016 (SCI-Expanded)

Publication Type: Article / Article
Volume: 26 Issue: 2
Publication Date: 2016
Doi Number: 10.5455/bcp.20151003060610
Journal Name: KLINIK PSIKOFARMAKOLOJI BULTENI-BULLETIN OF CLINICAL PSYCHOPHARMACOLOGY
Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), TR DİZİN (ULAKBİM)
Page Numbers: pp.152-160
Keywords: CYP2C19 polymorphism, side effects, medication adherence, selective serotonin reuptake inhibitors, HUMAN LIVER-MICROSOMES, N-DEMETHYLATION, CYTOCHROME-P450 ENZYMES, ANTIDEPRESSANT TREATMENT, PSYCHIATRIC-PATIENTS, IN-VITRO, SERTRALINE, GENOTYPE, DEPRESSION, CITALOPRAM
Marmara University Affiliated: Yes

Abstract

Objective: The aim of this study is to determine relationship of cytochrome P-450 2C19 (CYP2C19) enzymes polymorphism, side effects, and medication adherence in patients who have been diagnosed with major depression and have utilized selective serotonin reuptake inhibitors.