Influence of rosuvastatin treatment on airway inflammatory markers and health related quality of life domains in asthmatic patients

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OLGUN YILDIZELİ Ş. , Kocakaya D. , Balcan B. , Ikinci A., Ahiskali R., CEYHAN B.

MARMARA MEDICAL JOURNAL, vol.30, no.2, pp.73-81, 2017 (Journal Indexed in ESCI) identifier identifier

  • Publication Type: Article / Article
  • Volume: 30 Issue: 2
  • Publication Date: 2017
  • Doi Number: 10.5472/marumj.344816
  • Title of Journal : MARMARA MEDICAL JOURNAL
  • Page Numbers: pp.73-81
  • Keywords: Asthma, Airway inflammation, Remodelling, Rosuvastatin, Statin, NECROSIS-FACTOR-ALPHA, HMG-COA REDUCTASE, ALLERGIC-ASTHMA, IN-VITRO, STATINS, ATORVASTATIN, SIMVASTATIN, INHIBITORS, SPUTUM

Abstract

Objectives: Statins are lipid lowering agents which have pleiotropic and anti-inflammatory effects. Beneficial effects of statins have been shown in many inflammatory and asthmatic diseases. However, the results are still not consistent. The aim of this study is to determine the clinical and anti-inflammatory effects of rosuvastatin in asthmatic patients.