Influence of rosuvastatin treatment on airway inflammatory markers and health related quality of life domains in asthmatic patients

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OLGUN YILDIZELİ Ş., Kocakaya D., Balcan B., Ikinci A., Ahiskali R., CEYHAN B.

MARMARA MEDICAL JOURNAL, cilt.30, sa.2, ss.73-81, 2017 (ESCI) identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 30 Sayı: 2
  • Basım Tarihi: 2017
  • Doi Numarası: 10.5472/marumj.344816
  • Dergi Adı: MARMARA MEDICAL JOURNAL
  • Derginin Tarandığı İndeksler: Emerging Sources Citation Index (ESCI), Scopus, TR DİZİN (ULAKBİM)
  • Sayfa Sayıları: ss.73-81
  • Anahtar Kelimeler: Asthma, Airway inflammation, Remodelling, Rosuvastatin, Statin, NECROSIS-FACTOR-ALPHA, HMG-COA REDUCTASE, ALLERGIC-ASTHMA, IN-VITRO, STATINS, ATORVASTATIN, SIMVASTATIN, INHIBITORS, SPUTUM
  • Marmara Üniversitesi Adresli: Evet

Özet

Objectives: Statins are lipid lowering agents which have pleiotropic and anti-inflammatory effects. Beneficial effects of statins have been shown in many inflammatory and asthmatic diseases. However, the results are still not consistent. The aim of this study is to determine the clinical and anti-inflammatory effects of rosuvastatin in asthmatic patients.