Introduction: We aimed to evaluate left ventricular (LV) and right ventricular (RV) systolic performance in
patients with sepsis or septic shock and possible functional alteration on in-hospital mortality.
Patients and Methods: Thirty-seven consecutive patients with the diagnosis of sepsis or septic shock were
included in the study. All patients underwent comprehensive transthoracic echocardiographic examination.
Data of patients discharged from the intensive care unit was compared with data of patients who died in the
Results: Fifteen patients (40.5%) survived, while 22 patients were died in the hospital (59.5%). A significant difference was detected between survivor and non-survivor groups regarding before discharge
or death level of inflammatory markers such as CRP (p= 0.05) and procalcitonin (p= 0.03) besides BNP
(p= 0.01) and SOFA (p= 0.009) score. There were two patients (5.4%) with EF value less than %50 in the
study population. Eight patients (21.6%) displayed hypokinesia on the apical segment, and four patients
(10.8%) had TAPSE values below 17 mm. One patient (6.6%) in the survivor group, but seven patients
(31.8%) in the non-survivor group had apical hypokinesia with a trend towards significance (p= 0.068).
One patient in the survivor group (6.6%) and three patients (13.6%) in the non-survivor group had RV
systolic dysfunction (p= 0.51).
Conclusion: We found a much lower rate of LV and RV systolic dysfunction in patients with sepsis or septic
shock compared with previous studies. None of the myocardial dysfunction types was associated with in-hospital mortality. Apical hypokinesia was also more prevalent in non-survivors despite borderline significance.