Effect of low- and high-dose levothyroxine on thyroid nodule volume: a crossover placebo-controlled trial

Koc M., Ersoz H., Akpinar I., Gogas-Yavuz D., Deynell O., Akalin S.

CLINICAL ENDOCRINOLOGY, vol.57, no.5, pp.621-628, 2002 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 57 Issue: 5
  • Publication Date: 2002
  • Doi Number: 10.1046/j.1365-2265.2002.01650.x
  • Journal Name: CLINICAL ENDOCRINOLOGY
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.621-628
  • Marmara University Affiliated: Yes

Abstract

OBJECTIVE The efficacy and the effective dose of levothyroxine suppressive therapy in the treatment of benign thyroid nodules are controversial. In this study, we aimed to determine the response of solitary thyroid nodules to low- or high-level TSH suppression in a placebo-controlled, randomized crossover trial.