Tissue factor activities of streptozotocin induced diabetic rat tissues and the effect of peanut consumption

Emekli-Alturfan E. I., Kasikci E., Yarat A.

DIABETES-METABOLISM RESEARCH AND REVIEWS, cilt.23, sa.8, ss.653-658, 2007 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 23 Sayı: 8
  • Basım Tarihi: 2007
  • Doi Numarası: 10.1002/dmrr.757
  • Dergi Adı: DIABETES-METABOLISM RESEARCH AND REVIEWS
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.653-658
  • Marmara Üniversitesi Adresli: Evet

Özet

Background Tissue factor (TF) is considered to be a major regulator of normal haemostasis and thrombosis. Circulating TF activity is suggested to be associated with diabetes mellitus. Various tissues and body fluids have TF activity. The aim of the present study was to investigate the TF activity of streptozotocin (STZ) induced diabetic rat tissues. Peanut consumption is reported to be associated with decreased risk of type 2 diabetes. Therefore, the effect of peanut consumption on the TF activity of STZ induced diabetic rat tissues, and haemostatic parameters such as protrombin time (PT), activated partial thromboplastin time (APTT) and fibrinogen levels were determined.