Evaluation of the Effects of Donepezil, Memantine and alpha-lipoic Acid Combined Administration in Amnesia Rats on Impaired Cognitive Functions in Terms of Behavioural, Apoptotic, Cholinergic and Glutamatergic Systems
CLINICAL AND EXPERIMENTAL HEALTH SCIENCES, vol.11, no.4, pp.733-741, 2021 (Journal Indexed in ESCI)
Article / Article
Title of Journal :
CLINICAL AND EXPERIMENTAL HEALTH SCIENCES
Alpha-lipoic acid, amnesia, apoptosis, scopolamine, Y-maze, INDUCED MEMORY IMPAIRMENT, NEUROTROPHIC FACTOR, MUSCARINIC RECEPTORS, OXIDATIVE STRESS, SUBTYPES, MODEL, INFLAMMATION, ANTIOXIDANT, HIPPOCAMPUS, MECHANISMS
Objective: The aim of the study was to evaluate the possible protective effect of donepezil, memantine and alpha-lipoic acid (alpha-LA) combined therapy in the scopolamine-induced amnesia rat model.