Diagnostic Usage of Intracellular Protein Staining by Flow Cytometer in Primary Immune Deficiencies; Marmara Experience

ÖĞÜLÜR İ., BARIŞ S., Ozen A. O., Nain E., Kiykim A., Karakoc-Aydiner E.

ASTIM ALLERJI IMMUNOLOJI, vol.16, no.2, pp.81-89, 2018 (ESCI) identifier

  • Publication Type: Article / Article
  • Volume: 16 Issue: 2
  • Publication Date: 2018
  • Doi Number: 10.21911/aai.369
  • Journal Name: ASTIM ALLERJI IMMUNOLOJI
  • Journal Indexes: Emerging Sources Citation Index (ESCI), TR DİZİN (ULAKBİM)
  • Page Numbers: pp.81-89
  • Marmara University Affiliated: Yes

Abstract

Objective: The aim of our study was the optimization and standardization of intracellular dedicator of cytokinesis 8 (DOCK8), LPS-responsive beige-like anchor protein (LRBA), SH2D1A/SLAM-ssociated protein (SAP) and X-linked inhibitor of apoptosis protein (XIAP) protein expressions in healthy controls with a single flow cytometer protocol and to concomitantly evaluate the possible use of this method for diagnosis.