A novel approach in allergen-specific immunotherapy: Combination of sublingual and subcutaneous routes

Keles, Sevgi; Karakoc-Aydiner, ELİF; Ozen, AHMET; Izgi, Ayse; Tevetoglu, Ayzer; AKKOÇ, TUNÇ; Bahceciler, Nerin; Barlan, Isil

doi:10.1016/j.jaci.2011.04.033

A novel approach in allergen-specific immunotherapy: Combination of sublingual and subcutaneous routes

Keles S., Karakoc-Aydiner E. , Ozen A. O. , Izgi A. G. , Tevetoglu A., AKKOÇ T. , ...More

JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY, vol.128, no.4, pp.808-822, 2011 (Journal Indexed in SCI)

Publication Type: Article / Article
Volume: 128 Issue: 4
Publication Date: 2011
Doi Number: 10.1016/j.jaci.2011.04.033
Title of Journal : JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY
Page Numbers: pp.808-822

Abstract

Background: Subcutaneous allergen-specific immunotherapy (SIT) has an early onset of action, whereas repeated injections and safety concerns have limited its use in the pediatric age group. Meanwhile, the improved safety profile of the sublingual route has been accepted as an alternative despite its relatively late onset of action.