JOURNAL OF CLINICAL RESEARCH IN PEDIATRIC ENDOCRINOLOGY, vol.8, no.4, pp.452-460, 2016 (Journal Indexed in SCI)
Article / Article
Title of Journal :
JOURNAL OF CLINICAL RESEARCH IN PEDIATRIC ENDOCRINOLOGY
Cytokine signaling, polymorphism, obesity, children, TURKISH CHILDREN, INSULIN-RESISTANCE, METABOLIC SYNDROME, HEPATIC STEATOSIS, SOCS-3 GENE, ADOLESCENTS, SUPPRESSOR, PROMOTER, INFLAMMATION, EXPRESSION
Objective: Although polymorphisms in suppressor of cytokine signaling 3 (SOCS3) was reported to be related to obesity, Metabolic syndrome (MS), and type 2 diabetes mellitus in various adult studies, there is a lack of data in children. In this study, we examined eight reported polymorphisms of SOCS3 in obese Turkish children and adolescent with and without MS and compared the results with that of controls.