Effects of dapagliflozin in experimental sepsis model in rats

Kıngır Z. B., ÖZDEMİR KUMRAL Z. N., ÇAM M. E., KAYA Ö. T., ŞEKERLER T., ERCAN F., ...More

ULUSAL TRAVMA VE ACIL CERRAHI DERGISI-TURKISH JOURNAL OF TRAUMA & EMERGENCY SURGERY, vol.25, no.3, pp.213-221, 2019 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 25 Issue: 3
  • Publication Date: 2019
  • Doi Number: 10.5505/tjtes.2018.82826
  • Journal Name: ULUSAL TRAVMA VE ACIL CERRAHI DERGISI-TURKISH JOURNAL OF TRAUMA & EMERGENCY SURGERY
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus, TR DİZİN (ULAKBİM)
  • Page Numbers: pp.213-221
  • Keywords: Apoptosis, dapagliflozin, inflammation, oxidative stress, sepsis, ACUTE LUNG INJURY, NF-KAPPA-B, CECAL LIGATION, OXIDATIVE STRESS, SYSTEMIC INFLAMMATION, KIDNEY, PIOGLITAZONE, INHIBITION, PUNCTURE, GLUCOSE
  • Marmara University Affiliated: Yes

Abstract

BACKGROUND: The aim of this study was to evaluate the possible protective effects of dapagliflozin in an experimental sepsis model in rats.