A system based network approach to ethanol tolerance in Saccharomyces cerevisiae

Kasavi C., Eraslan S., ARĞA K. Y., Oner E. T., KIRDAR B.

BMC SYSTEMS BIOLOGY, cilt.8, 2014 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 8
  • Basım Tarihi: 2014
  • Doi Numarası: 10.1186/s12918-014-0090-6
  • Dergi Adı: BMC SYSTEMS BIOLOGY
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Anahtar Kelimeler: Ethanol tolerance network, Candidate genes, Saccharomyces cerevisiae, Protein-protein interaction network, CELL-GROWTH, PROTEIN, YEAST, GENE, MODULARITY, IDENTIFICATION, STRESS, FERMENTATION, FAMILY, LOCALIZATION
  • Marmara Üniversitesi Adresli: Evet

Özet

Background: Saccharomyces cerevisiae has been widely used for bio-ethanol production and development of rational genetic engineering strategies leading both to the improvement of productivity and ethanol tolerance is very important for cost-effective bio-ethanol production. Studies on the identification of the genes that are up-or down-regulated in the presence of ethanol indicated that the genes may be involved to protect the cells against ethanol stress, but not necessarily required for ethanol tolerance.