Treatment with estrogen receptor agonist ERβ improves torsion-induced oxidative testis injury in rats.


Tamer S. , YILDIRIM A. , Arabaci S., Ciftci S., Akin S., Sari E., ...More

Life sciences, vol.222, pp.203-211, 2019 (Journal Indexed in SCI Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 222
  • Publication Date: 2019
  • Doi Number: 10.1016/j.lfs.2019.02.056
  • Title of Journal : Life sciences
  • Page Numbers: pp.203-211
  • Keywords: Testicular torsion, Estrogen, Infertility, Sperm, Apoptosis, Oxidative injury, ISCHEMIA-REPERFUSION, TESTICULAR TORSION, GENE-EXPRESSION, NITRIC-OXIDE, ALPHA, MECHANISMS, AROMATASE, PARAMETERS, APOPTOSIS, LIGANDS

Abstract

Aims: The purpose of the present study was to investigate the potential antioxidant, anti-apoptotic and sperm function-preserving effects of estrogen, estrogen receptor (ER) a and ER beta agonists in a rat model of testis torsion-detorsion (T/D).