New in vitro effects of clopidogrel on platelets in hyperlipidemic and healthy subjects

ÖZSAVCI D., ŞENER A., OBA R., Demirel G. Y., Uras F., Yardimci T. K.

TURKISH JOURNAL OF HEMATOLOGY, cilt.27, sa.2, ss.99-108, 2010 (SCI-Expanded) identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 27 Sayı: 2
  • Basım Tarihi: 2010
  • Doi Numarası: 10.5152/tjh.2010.07
  • Dergi Adı: TURKISH JOURNAL OF HEMATOLOGY
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, TR DİZİN (ULAKBİM)
  • Sayfa Sayıları: ss.99-108
  • Anahtar Kelimeler: Platelets, hyperlipidemia, clopidogrel, apolipoprotein A1, apolipoprotein B, oxidative stress, nitrites, phosphatidylserine, P-selectin, glycoproteins IIb/IIIa, LOW-DENSITY-LIPOPROTEIN, GLYCOPROTEIN IIB/IIIA, P-SELECTIN, NORMOLIPEMIC VOLUNTEERS, SECONDARY PREVENTION, ACTIVATED PLATELETS, BINDING, INHIBITION, EXPRESSION, APOPTOSIS
  • Marmara Üniversitesi Adresli: Evet

Özet

Objective: We aimed to detect novel in vitro effects of clopidogrel on platelets by assessment of the following parameters: malondialdehyde, glutathione, nitrite, aggregation response, and expressions of P-selectin, fibrinogen, apolipoprotein A1, apolipoprotein B, and phosphatidylserine.